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Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria
Mutations in copper/zinc superoxide dismutase (SOD1) are causative for dominantly inherited amyotrophic lateral sclerosis (ALS). Despite high variability in biochemical properties among the disease-causing mutants, a proportion of both dismutase-active and -inactive mutants are stably bound to spina...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268797/ https://ncbi.nlm.nih.gov/pubmed/18296640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712209105 |
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