TP53 status and taxane-platinum versus platinum-based therapy in ovarian cancer patients: A non-randomized retrospective study

BACKGROUND: Taxane-platinum therapy (TP) has replaced platinum-based therapy (PC or PAC, DNA damaging chemotherapy) in the postoperative treatment of ovarian cancer patients; however, it is not always effective. TP53 protein plays a differential role in response to DNA-damaging agents and taxanes. W...

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Main Authors: Kupryjanczyk, Jolanta, Kraszewska, Ewa, Ziolkowska-Seta, Izabela, Madry, Radoslaw, Timorek, Agnieszka, Markowska, Janina, Stelmachow, Jerzy, Bidzinski, Mariusz
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268700/
https://ncbi.nlm.nih.gov/pubmed/18230133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-27
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