Spontaneous apoptosis in ovarian carcinomas: a positive association with p53 gene mutation is dependent on growth fraction

Changes in cell survival contribute to tumour development, influence tumour biology and its response to chemotherapy. p53 gene alterations should negatively affect apoptosis by impaired p53-dependent apoptotic response. We looked for associations between spontaneous apoptosis, p53 gene mutation, p53...

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Библиографические подробности
Главные авторы: Kupryjánczyk, J, Dansonka-Mieszkowska, A, Szymánska, T, Karpínska, G, Rembiszewska, A, Rusin, M, Konopínski, R, Kraszewska, E, Timorek, A, Yandell, D W, Stelmachów, J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2000
Предметы:
Regular Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363315/
https://ncbi.nlm.nih.gov/pubmed/10682669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0967
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