Spontaneous apoptosis in ovarian carcinomas: a positive association with p53 gene mutation is dependent on growth fraction

Changes in cell survival contribute to tumour development, influence tumour biology and its response to chemotherapy. p53 gene alterations should negatively affect apoptosis by impaired p53-dependent apoptotic response. We looked for associations between spontaneous apoptosis, p53 gene mutation, p53...

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Bibliografski detalji
Glavni autori: Kupryjánczyk, J, Dansonka-Mieszkowska, A, Szymánska, T, Karpínska, G, Rembiszewska, A, Rusin, M, Konopínski, R, Kraszewska, E, Timorek, A, Yandell, D W, Stelmachów, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2000
Teme:
Regular Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363315/
https://ncbi.nlm.nih.gov/pubmed/10682669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0967
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