The atypical mammalian ligand Delta-like homologue 1 (Dlk1) can regulate Notch signalling in Drosophila

BACKGROUND: Mammalian Delta-like 1 (Dlk-1) protein shares homology with Notch ligands but lacks a critical receptor-binding domain. Thus it is unclear whether it is able to interact with Notch in vivo. Unlike mammals, Drosophila have a single Notch receptor allowing a simple in vivo assay for mammal...

Full description

Saved in:
Bibliographic Details
Main Authors: Bray, Sarah J, Takada, Shuji, Harrison, Emma, Shen, Shing-Chuan, Ferguson-Smith, Anne C
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268666/
https://ncbi.nlm.nih.gov/pubmed/18237417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-8-11
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items