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Gene Dosage Effects of the Imprinted Delta-Like Homologue 1 (Dlk1/Pref1) in Development: Implications for the Evolution of Imprinting

Genomic imprinting is a normal process that causes genes to be expressed according to parental origin. The selective advantage conferred by imprinting is not understood but is hypothesised to act on dosage-critical genes. Here, we report a unique model in which the consequences of a single, double,...

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Main Authors: Teixeira da Rocha, Simao, Charalambous, Marika, Lin, Shau-Ping, Gutteridge, Isabel, Ito, Yoko, Gray, Dionne, Dean, Wendy, Ferguson-Smith, Anne C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640098/
https://ncbi.nlm.nih.gov/pubmed/19247431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000392
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