HLA alleles determine differences in human natural killer cell responsiveness and potency

Epidemiological studies have associated certain human disease outcomes with particular killer cell Ig-like receptor (KIR) and HLA genotypes. However, the functional explanation for these associations is poorly understood, because the KIRs were initially described as natural killer (NK) cell inhibito...

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Main Authors: Kim, Sungjin, Sunwoo, John B., Yang, Liping, Choi, Taewoong, Song, Yun-Jeong, French, Anthony R., Vlahiotis, Anna, Piccirillo, Jay F., Cella, Marina, Colonna, Marco, Mohanakumar, Thalachallour, Hsu, Katharine C., Dupont, Bo, Yokoyama, Wayne M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2008
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268583/
https://ncbi.nlm.nih.gov/pubmed/18287063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712229105
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