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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity
There are many inhibitory mechanisms that function at the cellular and molecular levels to maintain tolerance. Despite this, self-reactive clones escape regulatory mechanisms and cause autoimmunity in certain circumstances. We hypothesized that the same mechanisms that permit T cells to expand durin...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268574/ https://ncbi.nlm.nih.gov/pubmed/18287017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712135105 |
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