Paradoxical CD4 Lymphopenia in Autoimmune Lymphoproliferative Syndrome (ALPS)

Autoimmune lymphoproliferative syndrome (ALPS) is caused by germline or somatic loss of function FAS mutations resulting in impaired apoptosis and consequent expansion of T-lymphocytes causing organomegaly and autoimmune anemia, neutropenia and thrombocytopenia. Herein, we report on a case of dissem...

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Publicat a:Front Immunol
Autors principals: Lisco, Andrea, Wong, Chun-Shu, Price, Susan, Ye, Peiying, Niemela, Julie, Anderson, Megan, Richards, Elizabeth, Manion, Maura, Mystakelis, Harry, Similuk, Morgan, Lo, Bernice, Stoddard, Jennifer, Rosenzweig, Sergio, Vanpouille, Christophe, Rupert, Adam, Maric, Irina, Perez-Diez, Ainhoa, Parenti, David, Burbelo, Peter D., Rao, V. Koneti, Sereti, Irini
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549489/
https://ncbi.nlm.nih.gov/pubmed/31191551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01193
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