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A systems approach to delineate functions of paralogous transcription factors: Role of the Yap family in the DNA damage response

Duplication of genes encoding transcription factors plays an essential role in driving phenotypic variation. Because regulation can occur at multiple levels, it is often difficult to discern how each duplicated factor achieves its regulatory specificity. In these cases, a “systems approach” may dist...

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Hlavní autoři: Tan, Kai, Feizi, Hoda, Luo, Colin, Fan, Stephanie H., Ravasi, Timothy, Ideker, Trey G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268563/
https://ncbi.nlm.nih.gov/pubmed/18287073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708670105
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