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A systems approach to delineate functions of paralogous transcription factors: Role of the Yap family in the DNA damage response

Duplication of genes encoding transcription factors plays an essential role in driving phenotypic variation. Because regulation can occur at multiple levels, it is often difficult to discern how each duplicated factor achieves its regulatory specificity. In these cases, a “systems approach” may dist...

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Detalhes bibliográficos
Main Authors: Tan, Kai, Feizi, Hoda, Luo, Colin, Fan, Stephanie H., Ravasi, Timothy, Ideker, Trey G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268563/
https://ncbi.nlm.nih.gov/pubmed/18287073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708670105
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