Coevolution within a transcriptional network by compensatory trans and cis mutations

Transcriptional networks have been shown to evolve very rapidly, prompting questions as to how such changes arise and are tolerated. Recent comparisons of transcriptional networks across species have implicated variations in the cis-acting DNA sequences near genes as the main cause of divergence. Wh...

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Bibliographic Details
Main Authors: Kuo, Dwight, Licon, Katherine, Bandyopadhyay, Sourav, Chuang, Ryan, Luo, Colin, Catalana, Justin, Ravasi, Timothy, Tan, Kai, Ideker, Trey
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2010
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989993/
https://ncbi.nlm.nih.gov/pubmed/20978140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.111765.110
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