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Phosphorylation of Human Jak3 at Tyrosines 904 and 939 Positively Regulates Its Activity
Janus tyrosine kinase 3 (Jak3) is essential for signaling by interleukin-2 (IL-2) family cytokines and proper immune function. Dysfunctional regulation of Jak3 may result in certain disease states. However, the molecular mechanisms governing Jak3 activation are not fully understood. In this study, w...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268424/ https://ncbi.nlm.nih.gov/pubmed/18250158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01789-07 |
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