Genetic Modulation of the Overexpression of Tailoring Genes eryK and eryG Leading to the Improvement of Erythromycin A Purity and Production in Saccharopolyspora erythraea Fermentation

Erythromycin A (Er-A) is the most potent and clinically important member in the Er family produced by Saccharopolyspora erythraea. Er-B and Er-C, which are biologically much less active and cause greater side effects than Er-A, serve as the intermediates for Er-A biosynthesis and impurities in ferme...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chen, Yun, Deng, Wei, Wu, Jiequn, Qian, Jiangchao, Chu, Ju, Zhuang, Yingping, Zhang, Siliang, Liu, Wen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology (ASM) 2008
विषय:
Physiology and Biotechnology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268306/
https://ncbi.nlm.nih.gov/pubmed/18223111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02770-07
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