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Dissection of the insulin signaling pathway via quantitative phosphoproteomics

The insulin signaling pathway is of pivotal importance in metabolic diseases, such as diabetes, and in cellular processes, such as aging. Insulin activates a tyrosine phosphorylation cascade that branches to create a complex network affecting multiple biological processes. To understand the full spe...

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Detalhes bibliográficos
Main Authors: Krüger, Marcus, Kratchmarova, Irina, Blagoev, Blagoy, Tseng, Yu-Hua, Kahn, C. Ronald, Mann, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268157/
https://ncbi.nlm.nih.gov/pubmed/18268350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711713105
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