Progenitor/stem cells give rise to liver cancer due to aberrant TGF-β and IL-6 signaling

Cancer stem cells (CSCs) are critical for the initiation, propagation, and treatment resistance of multiple cancers. Yet functional interactions between specific signaling pathways in solid organ “cancer stem cells,” such as those of the liver, remain elusive. We report that in regenerating human li...

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Detalhes bibliográficos
Main Authors: Tang, Yi, Kitisin, Krit, Jogunoori, Wilma, Li, Cuiling, Deng, Chu-Xia, Mueller, Susette C., Ressom, Habtom W., Rashid, Asif, He, Aiwu Ruth, Mendelson, Jonathan S., Jessup, John M., Shetty, Kirti, Zasloff, Michael, Mishra, Bibhuti, Reddy, E. P., Johnson, Lynt, Mishra, Lopa
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268156/
https://ncbi.nlm.nih.gov/pubmed/18263735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705395105
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