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Rapid selection of accessible and cleavable sites in RNA by Escherichia coli RNase P and random external guide sequences
A method of inhibiting the expression of particular genes by using external guide sequences (EGSs) has been improved in its rapidity and specificity. Random EGSs that have 14-nt random sequences are used in the selection procedure for an EGS that attacks the mRNA for a gene in a particular location....
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268140/ https://ncbi.nlm.nih.gov/pubmed/18263737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711977105 |
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