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Inhibition of expression of virulence genes of Yersinia pestis in Escherichia coli by external guide sequences and RNase P

External guide sequences (EGSs) targeting virulence genes from Yersinia pestis were designed and tested in vitro and in vivo in Escherichia coli. Linear EGSs and M1 RNA-linked EGSs were designed for the yscN and yscS genes that are involved in type III secretion in Y. pestis. RNase P from E. coli cl...

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Autors principals: Ko, Jae-hyeong, Izadjoo, Mina, Altman, Sidney
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491477/
https://ncbi.nlm.nih.gov/pubmed/18567813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1120508
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