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Inhibition of expression of virulence genes of Yersinia pestis in Escherichia coli by external guide sequences and RNase P
External guide sequences (EGSs) targeting virulence genes from Yersinia pestis were designed and tested in vitro and in vivo in Escherichia coli. Linear EGSs and M1 RNA-linked EGSs were designed for the yscN and yscS genes that are involved in type III secretion in Y. pestis. RNase P from E. coli cl...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2491477/ https://ncbi.nlm.nih.gov/pubmed/18567813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1120508 |
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