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Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspects
IL-6-type cytokines bind to plasma membrane receptor complexes containing the common signal transducing receptor chain gp130 that is ubiquitously expressed in most tissues including the heart. The two major signalling cascades activated by the gp130 receptor, SHP2/ERK and STAT pathways, have been de...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268054/ https://ncbi.nlm.nih.gov/pubmed/18246092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.1 |
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