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The roles of the prostaglandin D(2) receptors DP(1) and CRTH2 in promoting allergic responses
Prostaglandin D(2) (PGD(2)) is produced by mast cells, Th2 lymphocytes and dendritic cells and has been detected in high concentrations at sites of allergic inflammation. PGD(2) exerts its inflammatory effects through high affinity interactions with the G protein coupled receptors DP(1) and chemoatt...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268053/ https://ncbi.nlm.nih.gov/pubmed/17965752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707488 |
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