The Efficacy of Tetracyclines in Peripheral and Intracerebral Prion Infection

We have previously shown that tetracyclines interact with and reverse the protease resistance of pathological prion protein extracted from scrapie-infected animals and patients with all forms of Creutzfeldt-Jakob disease, lowering the prion titre and prolonging survival of cerebrally infected animal...

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Main Authors: De Luigi, Ada, Colombo, Laura, Diomede, Luisa, Capobianco, Raffaella, Mangieri, Michela, Miccolo, Claudia, Limido, Lucia, Forloni, Gianluigi, Tagliavini, Fabrizio, Salmona, Mario
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2008
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268013/
https://ncbi.nlm.nih.gov/pubmed/18365024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001888
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