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Tetracyclines affect prion infectivity

Prion diseases are transmissible neurodegenerative disorders of humans and animals for which no effective treatment is available. Conformationally altered, protease-resistant forms of the prion protein (PrP) termed PrP(Sc) are critical for disease transmissibility and pathogenesis, thus representing...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Forloni, Gianluigi, Iussich, Selina, Awan, Tazeen, Colombo, Laura, Angeretti, Nadia, Girola, Laura, Bertani, Ilaria, Poli, Giorgio, Caramelli, Maria, Grazia Bruzzone, Maria, Farina, Laura, Limido, Lucia, Rossi, Giacomina, Giaccone, Giorgio, Ironside, James W., Bugiani, Orso, Salmona, Mario, Tagliavini, Fabrizio
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2002
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12149459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162195499
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