Tetracyclines affect prion infectivity

Prion diseases are transmissible neurodegenerative disorders of humans and animals for which no effective treatment is available. Conformationally altered, protease-resistant forms of the prion protein (PrP) termed PrP(Sc) are critical for disease transmissibility and pathogenesis, thus representing...

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Bibliographic Details
Main Authors: Forloni, Gianluigi, Iussich, Selina, Awan, Tazeen, Colombo, Laura, Angeretti, Nadia, Girola, Laura, Bertani, Ilaria, Poli, Giorgio, Caramelli, Maria, Grazia Bruzzone, Maria, Farina, Laura, Limido, Lucia, Rossi, Giacomina, Giaccone, Giorgio, Ironside, James W., Bugiani, Orso, Salmona, Mario, Tagliavini, Fabrizio
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC125061/
https://ncbi.nlm.nih.gov/pubmed/12149459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162195499
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