KEAP1 MODIFICATION AND NUCLEAR ACCUMULATION IN RESPONSE TO S-NITROSOCYSTEINE

Keap1 is a key regulator of the Nrf2 transcription factor which transactivates the Antioxidant Response Element (ARE) and upregulates numerous proteins involved in antioxidant defense. Under basal conditions, Keap1 targets Nrf2 for ubiquitination and proteolytic degradation and as such is responsibl...

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Detaylı Bibliyografya
Asıl Yazarlar: Buckley, Barbara J, Li, Sheng, Whorton, A. Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267934/
https://ncbi.nlm.nih.gov/pubmed/18062931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.10.055
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