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Acid-Sensing Ion Channels (ASICs) as Pharmacological Targets for Neurodegenerative Diseases

A significant drop of tissue pH or acidosis is a common feature of acute neurological conditions such as ischemic stroke, brain trauma, and epileptic seizures. Acid-sensing ion channels, or ASICs, are proton-gated cation channels widely expressed in peripheral sensory neurons and in the neurons of t...

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Bibliografische gegevens
Hoofdauteurs: Xiong, Zhi-Gang, Pignataro, Giuseppe, Li, Minghua, Chang, Su-youne, Simon, Roger P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267925/
https://ncbi.nlm.nih.gov/pubmed/17945532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2007.09.001
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