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Site-directed mutagenesis of Arginine282 suggests how protons and peptides are co-transported by rabbit PepT1
The mammalian proton-coupled peptide transporter PepT1 is the major route of uptake for dietary nitrogen, as well as the oral absorption of a number of drugs, including β-lactam antibiotics and angiotensin-converting enzyme inhibitors. Here we have used site-directed mutagenesis to investigate furth...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267855/ https://ncbi.nlm.nih.gov/pubmed/18037334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2007.10.010 |
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