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The transmembrane tyrosines Y56, Y91 and Y167 play important roles in determining the affinity and transport rate of the rabbit proton-coupled peptide transporter PepT1

The mammalian proton-coupled peptide transporter PepT1 is widely accepted as the major route of uptake for dietary nitrogen, as well as being responsible for the oral absorption of a number of classes of drugs, including β-lactam antibiotics and angiotensin-converting enzyme (ACE) inhibitors. Using...

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Detalhes bibliográficos
Main Authors: Pieri, Myrtani, Gan, Christine, Bailey, Patrick, Meredith, David
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510438/
https://ncbi.nlm.nih.gov/pubmed/19389486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2009.04.014
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