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Performance of AAV8 vectors expressing human factor IX from a hepatic-selective promoter following intravenous injection into rats
BACKGROUND: Vectors based on adeno-associated virus-8 (AAV8) have shown efficiency and efficacy for liver-directed gene therapy protocols following intravascular injection, particularly in relation to haemophilia gene therapy. AAV8 has also been proposed for gene therapy targeted at skeletal and car...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267784/ https://ncbi.nlm.nih.gov/pubmed/18312698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-6-9 |
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