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Accurate prediction of protein–protein interactions from sequence alignments using a Bayesian method

Accurate and large-scale prediction of protein–protein interactions directly from amino-acid sequences is one of the great challenges in computational biology. Here we present a new Bayesian network method that predicts interaction partners using only multiple alignments of amino-acid sequences of i...

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Autors principals: Burger, Lukas, van Nimwegen, Erik
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267735/
https://ncbi.nlm.nih.gov/pubmed/18277381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100203
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