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Accurate prediction of protein–protein interactions from sequence alignments using a Bayesian method

Accurate and large-scale prediction of protein–protein interactions directly from amino-acid sequences is one of the great challenges in computational biology. Here we present a new Bayesian network method that predicts interaction partners using only multiple alignments of amino-acid sequences of i...

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Detalhes bibliográficos
Main Authors: Burger, Lukas, van Nimwegen, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267735/
https://ncbi.nlm.nih.gov/pubmed/18277381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100203
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