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Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake

High-affinity cellular copper uptake is mediated by the CTR (copper transporter) 1 family of proteins. The highly homologous hCTR (human CTR) 2 protein has been identified, but its function in copper uptake is currently unknown. To characterize the role of hCTR2 in copper homoeostasis, epitope-tagge...

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Detalhes bibliográficos
Main Authors: vandenBerghe, Peter V. E., Folmer, Dineke E., Malingré, Helga E. M., vanBeurden, Ellen, Klomp, Adriana E. M., vandeSluis, Bart, Merkx, Maarten, Berger, Ruud, Klomp, Leo W. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267400/
https://ncbi.nlm.nih.gov/pubmed/17617060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070705
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