Liver-Specific Commd1 Knockout Mice Are Susceptible to Hepatic Copper Accumulation

Canine copper toxicosis is an autosomal recessive disorder characterized by hepatic copper accumulation resulting in liver fibrosis and eventually cirrhosis. We have identified COMMD1 as the gene underlying copper toxicosis in Bedlington terriers. Although recent studies suggest that COMMD1 regulate...

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Detalhes bibliográficos
Main Authors: Vonk, Willianne I. M., Bartuzi, Paulina, de Bie, Prim, Kloosterhuis, Niels, Wichers, Catharina G. K., Berger, Ruud, Haywood, Susan, Klomp, Leo W. J., Wijmenga, Cisca, van de Sluis, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245254/
https://ncbi.nlm.nih.gov/pubmed/22216203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029183
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