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Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction

X-ray crystallography studies, as well as live-cell fluorescent imaging, have recently challenged the traditional view of protein kinase CK2. Unbalanced expression of catalytic and regulatory CK2 subunits has been observed in a variety of tissues and tumours. Thus the potential intersubunit flexibil...

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Autors principals: Laudet, Béatrice, Barette, Caroline, Dulery, Vincent, Renaudet, Olivier, Dumy, Pascal, Metz, Alexandra, Prudent, Renaud, Deshiere, Alexandre, Dideberg, Otto, Filhol, Odile, Cochet, Claude
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267368/
https://ncbi.nlm.nih.gov/pubmed/17714077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070825
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