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Enzyme substrate recognition in oxygen sensing: how the HIF trap snaps

The transcriptional activator HIF (hypoxia-inducible factor) is a focal point of biomedical research because many situations in physiology and in pathology coincide with hypoxia. The effects of HIF activation may be a facet of normal growth, as in embryonic development, they may counterbalance a dis...

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Hlavní autor: Metzen, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267343/
https://ncbi.nlm.nih.gov/pubmed/17990984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071306
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