Fortilin binds Ca(2+) and blocks Ca(2+)-dependent apoptosis in vivo

Fortilin, a 172-amino-acid polypeptide present both in the cytosol and nucleus, possesses potent anti-apoptotic activity. Although fortilin is known to bind Ca(2+), the biochemistry and biological significance of such an interaction remains unknown. In the present study we report that fortilin must...

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Autores principales: Graidist, Potchanapond, Yazawa, Michio, Tonganunt, Moltira, Nakatomi, Akiko, Lin, Curtis Chun-Jen, Chang, Jui-Yoa, Phongdara, Amornrat, Fujise, Ken
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2007
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267342/
https://ncbi.nlm.nih.gov/pubmed/17705784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070679
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