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Embryonic Lethality of Fortilin-null mutant mice by BMP-pathway overactivation
BACKGROUND: Fortilin negatively regulates apoptosis and is overexpressed in cancer. However, the role of fortilin in mammalian development is not clear. METHODS & RESULTS: In order to evaluate the physiological role of fortilin in vivo, we performed a targeted disruption of the fortilin gene in...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695948/ https://ncbi.nlm.nih.gov/pubmed/19364479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2009.01.012 |
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