Embryonic Lethality of Fortilin-null mutant mice by BMP-pathway overactivation

BACKGROUND: Fortilin negatively regulates apoptosis and is overexpressed in cancer. However, the role of fortilin in mammalian development is not clear. METHODS & RESULTS: In order to evaluate the physiological role of fortilin in vivo, we performed a targeted disruption of the fortilin gene in...

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Hlavní autoři: Koide, Yuichi, Kiyota, Tomomi, Tonganunt, Moltira, Pinkaew, Decha, Liu, Zhihe, Kato, Yoichi, Hutadilok-Towantana, Nongporn, Phongdara, Amornrat, Fujise, Ken
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695948/
https://ncbi.nlm.nih.gov/pubmed/19364479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2009.01.012
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