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Age-associated perturbations in glutathione synthesis in mouse liver

The nature of the mechanisms underlying the age-related decline in glutathione (GSH) synthetic capacity is at present unclear. Steady-state kinetic parameters of mouse liver GCL (glutamate–cysteine ligase), the rate-limiting enzyme in GSH synthesis, and levels of hepatic GSH synthesis precursors fro...

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Bibliographic Details
Main Authors: Toroser, Dikran, Sohal, Rajindar S.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267299/
https://ncbi.nlm.nih.gov/pubmed/17461778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061868
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