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Role of transmembrane segment M8 in the biogenesis and function of yeast plasma-membrane H(+)-ATPase

Of the four transmembrane helices (M4, M5, M6, and M8) that pack together to form the ion-binding sites of P(2)-type ATPases, M8 has until now received the least attention. The present study has used alanine-scanning mutagenesis to map structure-function relationships throughout M8 of the yeast plas...

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Detalhes bibliográficos
Main Authors: Guerra, Guadalupe, Petrov, Valery V., Allen, Kenneth E., Miranda, Manuel, Pardo, Juan Pablo, Slayman, Carolyn W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267258/
https://ncbi.nlm.nih.gov/pubmed/17573037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2007.04.029
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