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C-Terminal Truncations of the Saccharomyces cerevisiae PMA1 H(+)-ATPase Have Major Impacts on Protein Conformation, Trafficking, Quality Control, and Function

The C-terminal tail of yeast plasma membrane (PM) H(+)-ATPase extends approximately 38 amino acids beyond the final membrane-spanning segment (TM10) of the protein and is known to be required for successful trafficking, stability, and regulation of enzyme activity. To carry out a detailed functional...

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Detalhes bibliográficos
Main Authors: Mason, A. Brett, Allen, Kenneth E., Slayman, Carolyn W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910955/
https://ncbi.nlm.nih.gov/pubmed/24186948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00201-13
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