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Malaria Liver Stage Susceptibility Locus Identified on Mouse Chromosome 17 by Congenic Mapping

Host genetic variants are known to confer resistance to Plasmodium blood stage infection and to control malaria severity both in humans and mice. This work describes the genetic mapping of a locus for resistance to liver stage parasite in the mouse. First, we show that decreased susceptibility to th...

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Bibliographische Detailangaben
Hauptverfasser: Gonçalves, Lígia Antunes, Almeida, Paulo, Mota, Maria Manuel, Penha-Gonçalves, Carlos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267218/
https://ncbi.nlm.nih.gov/pubmed/18365019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001874
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