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A Dual-Color Fluorescence-Based Platform to Identify Selective Inhibitors of Akt Signaling

BACKGROUND: Inhibition of Akt signaling is considered one of the most promising therapeutic strategies for many cancers. However, rational target-orientated approaches to cell based drug screens for anti-cancer agents have historically been compromised by the notorious absence of suitable control ce...

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Detalhes bibliográficos
Main Authors: Rosado, Aranzazú, Zanella, Fabian, Garcia, Beatriz, Carnero, Amancio, Link, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267216/
https://ncbi.nlm.nih.gov/pubmed/18350159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001823
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