Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels

Type II hexokinase is overexpressed in most neoplastic cells, and it mainly localizes on the outer mitochondrial membrane. Hexokinase II dissociation from mitochondria triggers apoptosis. The prevailing model postulates that hexokinase II release from its mitochondrial interactor, the voltage-depend...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chiara, Federica, Castellaro, Diego, Marin, Oriano, Petronilli, Valeria, Brusilow, William S., Juhaszova, Magdalena, Sollott, Steven J., Forte, Michael, Bernardi, Paolo, Rasola, Andrea
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2008
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267038/
https://ncbi.nlm.nih.gov/pubmed/18350175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001852
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