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Three Novel Missense Mutations within the LHX4 Gene Are Associated with Variable Pituitary Hormone Deficiencies
Context: The LHX4 LIM-homeodomain transcription factor has essential roles in pituitary gland and nervous system development. Heterozygous mutations in LHX4 are associated with combined pituitary hormone deficiency. Objectives: Our objectives were to determine the nature and frequency of LHX4 mutati...
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Main Authors: | , , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
The Endocrine Society
2008
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266965/ https://ncbi.nlm.nih.gov/pubmed/18073311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2007-1525 |
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