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Mutations in the LHX3 gene cause dysregulation of pituitary and neural target genes that reflect patient phenotypes
The LHX3 LIM-homeodomain transcription factor is required for correct development of the mammalian pituitary gland and spinal motoneurons. Mutations in the LHX3 gene underlie complex diseases featuring combined anterior pituitary hormone deficiency and, in specific cases, loss of neck rotation consi...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045125/ https://ncbi.nlm.nih.gov/pubmed/17616267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2007.05.017 |
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