Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant-negative mutant

cJun, a major constituent of AP-1 transcription factor transducing multiple mitogen growth signals, is frequently overexpressed in non-small cell lung cancers (NSCLCs). The purpose of this study is to determine the effects of AP-1 blockade on the growth of NSCLC cells using a cJun dominant-negative...

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Autores principales: Shimizu, Y, Kinoshita, I, Kikuchi, J, Yamazaki, K, Nishimura, M, Birrer, M J, Dosaka-Akita, H
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
Materias:
Translational Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266861/
https://ncbi.nlm.nih.gov/pubmed/18283312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604267
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