Genomic activation of the EGFR and HER2-neu genes in a significant proportion of invasive epithelial ovarian cancers

BACKGROUND: The status of the EGFR and HER2-neu genes has not been fully defined in ovarian cancer. An integrated analysis of both genes could help define the proportion of patients that would potentially benefit from targeted therapies. METHODS: We determined the tumour mutation status of the entir...

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Hlavní autoři: Vermeij, Joanna, Teugels, Erik, Bourgain, Claire, Xiangming, Ji, in 't Veld, Peter, Ghislain, Vanessa, Neyns, Bart, De Grève, Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266762/
https://ncbi.nlm.nih.gov/pubmed/18182111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-3
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