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A Ca(V)β SH3/Guanylate Kinase Domain Interaction Regulates Multiple Properties of Voltage-gated Ca(2+) Channels
Auxiliary Ca(2+) channel β subunits (Ca(V)β) regulate cellular Ca(2+) signaling by trafficking pore-forming α(1) subunits to the membrane and normalizing channel gating. These effects are mediated through a characteristic src homology 3/guanylate kinase (SH3–GK) structural module, a design feature s...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
The Rockefeller University Press
2005
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266626/ https://ncbi.nlm.nih.gov/pubmed/16186563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509354 |
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