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Functional dissection of the intramolecular Src homology 3-guanylate kinase domain coupling in voltage-gated Ca(2+) channel β-subunits
The β-subunit of voltage-gated Ca(2+) channels is essential for trafficking the channels to the plasma membrane and regulating their gating. It contains a Src homology 3 (SH3) domain and a guanylate kinase (GK) domain, which interact intramolecularly. We investigated the structural underpinnings of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739582/ https://ncbi.nlm.nih.gov/pubmed/19427861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.05.001 |
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