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Functional dissection of the intramolecular Src homology 3-guanylate kinase domain coupling in voltage-gated Ca(2+) channel β-subunits

The β-subunit of voltage-gated Ca(2+) channels is essential for trafficking the channels to the plasma membrane and regulating their gating. It contains a Src homology 3 (SH3) domain and a guanylate kinase (GK) domain, which interact intramolecularly. We investigated the structural underpinnings of...

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Détails bibliographiques
Auteurs principaux: Chen, Yu-hang, He, Lin-ling, Buchanan, Douglas R., Zhang, Yun, Fitzmaurice, Aileen, Yang, Jian
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739582/
https://ncbi.nlm.nih.gov/pubmed/19427861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.05.001
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