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A single Ca(V)β can reconstitute both trafficking and macroscopic conductance of voltage-dependent calcium channels
Voltage-dependent calcium-channel β subunits (Ca(V)β) strongly modulate pore-forming α(1) subunits by trafficking channel complexes to the plasma membrane and enhancing channel open probability (P(o)). Despite their central role, it is unclear whether binding of a single Ca(V)β, or multiple Ca(V)βs,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1474221/ https://ncbi.nlm.nih.gov/pubmed/16020456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.093195 |
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