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Electrostatics in the Cytoplasmic Pore Produce Intrinsic Inward Rectification in Kir2.1 Channels

Inward rectifier K(+) channels are important in regulating membrane excitability in many cell types. The physiological functions of these channels are related to their unique inward rectification, which has been attributed to voltage-dependent block. Here, we show that inward rectification can also...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yeh, Shih-Hao, Chang, Hsueh-Kai, Shieh, Ru-Chi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266598/
https://ncbi.nlm.nih.gov/pubmed/16316974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509367
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