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Retardation of skeletal development and cervical abnormalities in transgenic mice expressing a dominant-negative retinoic acid receptor in chondrogenic cells

Skeletal formation is a fundamental element of body patterning and is strictly regulated both temporally and spatially by a variety of molecules. Among these, retinoic acid (RA) has been shown to be involved in normal skeletal development. However, its pleiotropic effects have caused difficulty in i...

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Autores principales: Yamaguchi, Masahiro, Nakamoto, Mika, Honda, Hiroaki, Nakagawa, Toshiyuki, Fujita, Hiroshi, Nakamura, Takashi, Hirai, Hisamaru, Narumiya, Shuh, Kakizuka, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC22661/
https://ncbi.nlm.nih.gov/pubmed/9636177
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