Roles of Toll-like receptor 2/4, monoacylglycerol lipase, and cyclooxygenase in social defeat stress-induced prostaglandin E(2) synthesis in the brain and their behavioral relevance

Inflammation in the brain and periphery has been associated with stress-related pathology of mental illness. We have shown that prostaglandin (PG) E(2), an arachidonic acid-derived lipid mediator, and innate immune receptors Toll-like receptor (TLR) 2/4 are crucial for repeated stress-induced behavi...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Nie, Xiang, Kitaoka, Shiho, Shinohara, Masakazu, Kakizuka, Akira, Narumiya, Shuh, Furuyashiki, Tomoyuki
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879743/
https://ncbi.nlm.nih.gov/pubmed/31772309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54082-5
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